Understand your Alkaline Phosphatase (ALP) Blood Test Results…

This page helps you to understand blood test results for your ALP and gives you the reference range to determine if your lab test results mean that you a have high, low or normal ALP levels. 

We outline the risk factors associated with raised and low ALP levels.

Reference Ranges for ALP:

Measurement Units Metric Optimal Borderline Risk
US Conventional Units U/L 30-129 130-150 <30 or >150
Standard International Units U/L 30-129 130-150 <30 or >150
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What is Alkaline phosphatase (ALP)

ALP is an enzyme in the liver, bile ducts and bone. Liver cells release increased amounts of ALP into the blood when there is liver damage [37].

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Function of Alkaline phosphatase (ALP)

In the liver, ALP is found on the edges of cells that join to form bile ducts, tiny tubes that drain bile from the liver to the bowels, where it is needed to help digest fat in the diet. ALP in bone is produced by special cells called osteoblasts that are involved in the formation of bone [37].

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Risk factors associated with Alkaline phosphatase (ALP)

  • Higher-than-normal levels of ALP may indicate liver damage or disease.
  • This test is often used to detect blocked bile ducts because ALP is especially high in the edges of cells that join to form bile ducts. If one or more of them are obstructed then blood levels of ALP will often be high.
  • Any condition that affects bone growth or causes increased activity of bone cells can affect ALP levels in the blood. Values from 10 to 25 times the upper limit of the reference interval are not unusual in these cases [37].
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Notable variations by Demographic Group

An increase of 2 to 3 times normal may be observed in women in the third trimester of pregnancy, although the interval is very wide and levels may not exceed the upper limit of the reference interval in some cases. The additional enzyme is of placental origin [39].

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Diet to improve Alkaline phosphatase (ALP)

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Supplements for Alkaline phosphatase (ALP)

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Exercise to improve Alkaline phosphatase (ALP)

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Sleep for Alkaline phosphatase (ALP)