This page helps you to understand blood test results for your AG Ratio and gives you the reference range to determine if your lab test results mean that you a have high, low or normal AG Ratio.
We outline the risk factors associated with raised and low AG Ratio.
Reference Ranges for Total Protein:
|US Conventional Units||ratio||0.8-2||<0.8 or >2|
|Standard International Units||ratio||0.8-2||<0.8 or >2|
What is A/G Ratio
The albumin/globulin (A/G) ratio is the amount of albumin in the serum divided by the globulins. Because disease states affect the relative amounts of albumin and globulin, the A/G ratio may provide a clue as to the cause of the change in protein levels .
Function of A/G Ratio
See Albumin & Globulin pages for the function of these proteins
Risk factors associated with A/G Ratio
- A low A/G ratio may reflect overproduction of globulins, such as seen in multiple myeloma or autoimmune diseases, or underproduction of albumin, such as may occur with cirrhosis, or selective loss of albumin from the circulation, as may occur with kidney disease.
- A high A/G ratio suggests underproduction of immunoglobulins as may be seen in some genetic deficiencies.
- With a low total protein that is due to plasma expansion (dilution of the blood), the A/G ratio will typically be normal because both albumin and globulin will be diluted to the same extent .
Notable variations by Demographic Group
Low levels of albumin and globulin are more often seen in elderly patients .